Project 01.
miRNA expression, identification, and functional characterization under oxidative stress challenge in diabetic retinopathy.
Research projects and doctoral candidates
RETORNA aims to implement 10 research projects that will contribute to understanding retinal diseases and will give novel insights towards a potential RNA treatment.
Research Projects
Project 02.
Targeting of diabetic retinopathy by miRNA in a human retinal organoid model.
Project 03.
Expression of RNA based TrkB-aptamers for the treatment of age-related macular degeneration.
Project 04.
Study of microRNA expression profile in Central Areolar Choroidal Dystrophy. Translational study using a new CRISPR-generated animal model.
Project 05.
Designing of Novel Aptamer-Based AT1R Targeted Therapeutics Against Retinal Degeneration.
Project 06.
Prevention of premature photoreceptor cell death in CRB1 retinitis pigmentosa models by RNA modulation.
Project 07.
Examining Health Economic Impacts of RNA in treating retinal diseases.
Project 08.
CRISPR therapy in a retinal hereditary dystrophy. Translational study using an animal model and retinal organotypic cultures.
Project 09.
Evaluation by RNA-seq-based approaches of the global role of microRNAs and of other noncoding RNAs in the human and mouse retina in both physiological and pathological conditions (Inherited Retinal Disease).
Project 10.
Retinal miRNAs as molecular targets for the treatment of retinitis pigmentosa.
