Publications, posters and presentations

Explore the research outputs of RETORNA project:

International Journal of Molecular Sciences

Role of Exosomal miR-205-5p Cargo in Angiogenesis and Cell Migration

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EE384 Value in Health - UCC

EE384 The Economic Impact of Neovascular Age-Related Macular Degeneration (nAMD), Diabetic Retinopathy (DR), and Diabetic Macular Edema (DME): A Systematic Literature Review of the Emerging Literature

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The Future of Nanomaterials Tackling the Challenge of Delivering Nucleic Acids to the Retina

The Future of Nanomaterials Tackling the Challenge of Delivering Nucleic Acids to the Retina

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UCV publication Antioxidants

miR-205-5p Modulates High Glucose-Induced VEGFA Levels in Diabetic Mice and ARPE-19 Cells

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miR-429 RNA therapy as generic strategy to protect against photoreceptor loss

miR-429 RNA therapy as generic strategy to protect against photoreceptor loss

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Posters and presentations DC1

  • Inhibition of High Glucose-Induced Retinal Angiogenesis by miR-205-5p: Targeting HIF-1α and VEGFA Expression. Proretina Meeting 2024, Potsdam, 12th-13th April 2024.
  • miR-205-5p suppresses high glucose-induced angiogenesis in retinal cells. ARVO 2024, Seattle, 5th-9th May 2024.

 

Posters and presentations DC2

  • The long-term effects of hyperglycemia on human iPSC-derived retinal pigment epithelial cells. Dutch Ophthalmology PhD Students Conference – (DOPS), Nijmegen, 1st-2nd of November 2024.

 

Posters and presentations DC3

  • Establishing plasmid-mediated expression of RNA-based TrĸB-binding aptamers for the treatment of age-related macular degeneration. Proretina Meeting 2024, Potsdam, 12th-13th April 2024.
  • Aptamer-Based Neuroprotection in Retinal Organ Cultures. die 27. Chirurgischen Forschungstage 2024, Tübingen, 26th-28th September 2024 and iSearch, online, 15th-16th November 2024.
  • Expression of RNA-based TrkB-aptamers for the treatment of age-related macular degeneration. First progress report at Progress in Ophtalmic research, Tübingen, 2nd of October 2024 and Annual report and doctoral committee meeting, Tübingen, 10th of December 2024.
 
  • Prph2 mutant mice reveal differential gene expression profile related to visual cycle forward degeneration. Proretina Meeting 2024, Potsdam, 12th-13th April 2024.
  • PRPH2 knock-in mouse shows up regulated genes related to visual cycle and down regulated inflammatory pathways at early stages of the degeneration. ARVO 2024, Seattle, 5th-9th May 2024
  • The regulation of immune system is involved in PRPH2 knok-in mouse retinal degeneration. ARVO 2024, Seattle, 5th-9th May 2024
 

Posters and presentations DC5

  • Targeting AT1R with RNA Aptamers to manage Retinal Degeneration. 9th International BAU Drug Design Congress 2023, Istanbul, 29th November – 2nd December 2023.
  • Computational RNA Aptamer Design: A Pipeline of Precise Targeting of Macromolecular Elements in the Pursuit of Treating Retinal Degeneration within the RETORNA – A HORIZON Europe Initiative. 12th International Drug Chemistry Conference, Antalya, 7th-10th March 2024.
  • Papazoglou, I.; Yao, Y.; Tunc, H.; Hosseinzadeh, Z.; Durdagi, S. Tailored RNA-Therapeutics: Genetic Algorithm-Enhanced RNA Aptamer Discovery for Targeted Retinal Degeneration Therapy. EuroQSAR24, Barcelona, 22nd-26th September 2024.

 

Posters and presentations DC6

  • Prevention of premature photoreceptor cell death in CRB1 Retinitis Pigmentosa models by RNA modulation. Proretina Meeting 2024, Potsdam, 12th-13th April 2024 and ARVO 2024, Seattle, 5th-9th May 2024.

 

Posters and presentations DC7

  • The economic impact of inherited retinal diseases (IRDs): a systematic literature review. Proretina Meeting 2024, Potsdam, 12th-13th April 2024; CUBS Postgraduate Research Symposium, Cork, 24th of April 2024; Retina International World Congress 2024, Dublin, 5th-6th of June 2024.
  • The economic impact of neovascular age-related macular degeneration (nAMD), diabetic retinopathy (DR), and diabetic macular edema (DME): a systematic literature review of the emerging literature. ISPOR Europe 2024, Barcelona, 17th-20th of November 2024.

 

Posters and presentations DC8

  • Prph2 mutant mice reveal differential gene expression profile related to visual cycle forward degeneration. Proretina Meeting 2024, Potsdam, 12th-13th April 2024.
  • RNA-seq reveals differential expression of genes related to visual cycle in Prph2 Knock-in mice. ARVO 2024, Seattle, 5th-9th May 2024.
  • Cellular and Molecular Dysfunction in the Retina and Optic Nerve as an early biomarker of Parkinson’s Patients. SEHIT 2024, Alicante, 10th-13th September 2024.

 

Posters and presentations DC9

  • Gaining insights into the role of longnoncoding RNA in Inherited Retinal Disorders. PhD Days “University of Campania Luigi Vanvitelli”, Naples, 26th of September 2024.
  • Insights into the role of noncoding RNA in Inherited Retinal Disorders. TIGEM Retreat, Naples, 4th-6th November 2024.